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Natural Factors

PEA400, (Palmitoylethanolamide), 400 mg, 90 Vegetarian Capsules

4.7 · 1453 reviews
3,714 ₽

Dietary Supplement (Palmitoylethanolamide) For Occasional Pain & Discomfort Naturally Produced from Fractionated non-GMO Safflower Oil Highest Purity Suitable for Vegetarians/Vegans The Power of PhytoResponse™ PhytoResponse™ refers to plant foods and herbs that can modulate and positively influence the Endocannabinoid System (ECS) directly or indirectly and support the body’s production of endocannabinoids with non-cannabis, plant-based botanical compounds. ECS It's all about Balance. The ECS promotes homeostasis, or balance, which is what being healthy is all about. The Power of PEA and the Endocannabinoid System PEA (N-palmitoylethanolamide) is an endogenous fatty acid amide that belongs to the family of biologically active lipids that are increased by the body to soothe discomfort. PEA is a member of the ECS with several biological functions, including neuromodulatory activity in the central nervous system. It has been demonstrated to be effective on the different inflammatory mechanisms that develop and maintain both neurogenic and neuropathic pain. Pure PEA There are two sources of PEA commercially available. Synthetic forms require the use of powerful synthetic solvents. PEA can be naturally derived from safflower oil. PEA400 only utilizes naturally derived palmitoylethanolamide from safflower seed. PEA (palmitoylethanolamide) is a fatty-acid-like compound naturally found in foods. Natural Factors PEA is naturally produced from fractionated non-GMO safflower oil. It then undergoes a micronization process for improved solubility and absorption. PEA has been shown to be helpful in managing occasional pain and discomfort. Isura™: Non-GMO: Documentation Mass Spec: Lab Tested

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Dietary Supplement (Palmitoylethanolamide) For Occasional Pain & Discomfort Naturally Produced from Fractionated non-GMO Safflower Oil Highest Purity Suitable for Vegetarians/Vegans The Power of PhytoResponse™ PhytoResponse™ refers to plant foods and herbs that can modulate and positively influence the Endocannabinoid System (ECS) directly or indirectly and support the body’s production of endocannabinoids with non-cannabis, plant-based botanical compounds. ECS It's all about Balance. The ECS promotes homeostasis, or balance, which is what being healthy is all about. The Power of PEA and the Endocannabinoid System PEA (N-palmitoylethanolamide) is an endogenous fatty acid amide that belongs to the family of biologically active lipids that are increased by the body to soothe discomfort. PEA is a member of the ECS with several biological functions, including neuromodulatory activity in the central nervous system. It has been demonstrated to be effective on the different inflammatory mechanisms that develop and maintain both neurogenic and neuropathic pain. Pure PEA There are two sources of PEA commercially available. Synthetic forms require the use of powerful synthetic solvents. PEA can be naturally derived from safflower oil. PEA400 only utilizes naturally derived palmitoylethanolamide from safflower seed. PEA (palmitoylethanolamide) is a fatty-acid-like compound naturally found in foods. Natural Factors PEA is naturally produced from fractionated non-GMO safflower oil. It then undergoes a micronization process for improved solubility and absorption. PEA has been shown to be helpful in managing occasional pain and discomfort. Isura™: Non-GMO: Documentation Mass Spec: Lab Tested

Customer reviews

5.0
verified purchase
Helps with my nerve pain

I seemed to notice a difference in a couple of weeks but have been on it just over three weeks now and I am doing much better with my pain levels caused by a Tarlov cyst in the sacrum area. I like that there are no side effects. The capsules are easy to take with no taste.

2/6/2024
5.0
verified purchase
super

I’ve been taking this Natural Factors PEA supplement for a few weeks and I’m pleased with it. The capsules are easy to swallow and don’t upset my stomach. I feel more comfortable and less tension in my joints and muscles, especially after long days. It seems to support my overall sense of well-being. Overall — a good supplement that I plan to keep using

2/5/2026
5.0
verified purchase
A natural breakthrough for my nerve comfort.

I started taking PEA400 on the recommendation of my nutritionist for chronic nerve discomfort. Unlike other supplements I’ve tried, this actually worked without making me feel drowsy or upset my stomach. It took about two weeks of consistent use to 'build up' in my system, but the difference in my daily comfort levels is night and day. I love that it’s naturally produced in the body and that Natural Factors uses a high-quality, micronized source for better absorption.

12/17/2025
5.0
verified purchase
Natural Factors PEA400 Excellent

Great brand for vegetarians and vegans. Quality ingredients. Good supplement serving size. No taste. No side-effects. Works well, relieves symptoms. Benefits overall health. Nice package. Highly Recommend.

12/3/2025
5.0
verified purchase
Anti-inflammatory

This product is very effective for inflammation. The only complaint I have is the very large capsule that is difficult to swallow. It could easily be put into a smaller capsule as the existing capsule is not full.

12/1/2025
4.0
verified purchase
Pain Relief

I found this to take my chronic pain down a notch or two. Nothing super dramatic, but my pain just needs management sometimes. This seemed to work OK.

11/27/2025
4.0
verified purchase

Best quality ingredients used. Perfect size and dosage.Lots of benefit and leaves no after taste. I really like this Product , and would love to use it in the future as well. I like how it makes me feel, I really love the brand and its value.

11/20/2025
5.0
verified purchase
최고!

Quality is super! The ingredients are great! Size arranged! What you need! Performance is felt! the product arranged, perfectly packed, the effect is definitely there! I will order more! Just as quickly delivered

10/26/2025
5.0
verified purchase
PEA for Pain discomfort

I have been taking this for my nerve pain as an alternative to NSAID. So far it has worked for me so I will rate it as a good product. However, effects may differ from person to person. See improvement to the discomforts and since it’s natural I think its benefits is worth the try. All packaged in a well packed box and bottle - which is well sealed for assurance. Quality ingredients

10/19/2025
5.0
verified purchase
Works for me!

I have always trusted the quality of the products by natural factors, and this PEA supplement is no exception. PEA works for me, and will continue to purchase it for minor nerve discomfort.

10/7/2025