Longevity genes, also known as sirtuin genes. There are seven types of sirtuin genes. Seven types, from SIRT1 to SIRT7. Although there are seven types, the main one is SIRT1. Most anti-aging supplements, that is, supplements that focus on longevity genes, aim to activate SIRT1 (including increasing NAD+). Here, focusing on SIRT3 and SIRT6 in addition to SIRT1 is a step forward in anti-aging measures. SIRT3 is a sirtuin involved in oxidative stress control, and increases antioxidant power, leading to anti-aging. The antioxidant effect of SIRT3 is said to be effective for the ears (suppressing age-related hearing loss) and skin (suppressing excessive melanin production). That's enough of the introduction. This is a supplement that focuses on SIRT3, or rather, SIRT3 as well. I use the expression "also" because it contains NMN, so naturally you can expect SIRT1 activation by increasing NAD+. It is a product that is a little different from other anti-aging supplements.
Dietary Supplement NSF® Certified Sport Power up the powerhouse of your cells. Signal is designed to target metabolic aging by protecting mitochondria—where the energy in your cells is made. Increase NAD+ with the precursor NMN to support energy production and activate SIRT3, a key mitochondrial enzyme, to protect and generate new mitochondria and help your cells adapt to daily metabolic changes as you age.
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Dietary Supplement NSF® Certified Sport Power up the powerhouse of your cells. Signal is designed to target metabolic aging by protecting mitochondria—where the energy in your cells is made. Increase NAD+ with the precursor NMN to support energy production and activate SIRT3, a key mitochondrial enzyme, to protect and generate new mitochondria and help your cells adapt to daily metabolic changes as you age.
- SKU
- 3-146232
- Brand
- Elysium
- Category
- health / vitamins / vitamin-b-complex / vitamin-b3-niacin
- Variants
- 1
Customer reviews
The only product I noticed an actual difference and it doesn't contain any stimulants like caffeine so I take it while pregnant as well. I'm not sure how many people this will help but I have extremely light flows that last 2-3 days during my monthly cycle. On this I have healthier flow that last 4-5days. I was off of it for 6 months because I didn't have access to them and tried other NMN products that did not have the same effect. Found them on iHerb and I'm back. Love this product and highly recommend.
EDIT: I used to receive this in a jar, today it's in a packet. My last orders (prior to this) was Basis and Vision x2 (10th December 2025) - all were in a jar. I didn't pay $53 (after conversion from my local currency) just so you can be cheap on me with the packaging. At the very least you should reduce the price! And if you're phasing out the jars you should have at least made that clear with your iHerb international customers. AND YES, REDUCED THE PRICE!
Based on the studies I've read this is the best one out there!
Good ingredient as it labelled that to improve health level.
This product is a 1000/10! It makes your skin look so much younger. I took it in the morning along with Urolithin A. The product delivers on its promises regarding diet, sleep, activity, and this supplement changes your CPF (Brazilian tax identification number).
Great. Good size. Good quality. Great health benefits. Nice smell.
Great quality! awesome ingredients! feel the benefits! improvement in energetic. no taste. and good size and dosage. repeat customer!
A professional supplement, completely different from ordinary supplements. I noticed increased activity and sustained energy throughout the day. The quality is high, and the ingredient formula is potent and well-designed. It's ideal for those seeking advanced metabolic and cellular support. The price is slightly higher, but it's worth it.
I have been using Elysium products not just Signal but ALL the supplements they carry n its excellent. I used to tonorder them directly fr Elysium in US but now, with IHerb I receive them faster. Its the BEST product for staying healthy.
