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Natural Factors

Stress-Relax®, 5-HTP, 100 mg, 120 Time Release Caplets

4.7 · 880 reviews
3,900 ₽

Dietary Supplement 5-Hydroxytryptophan Emotional Well-Being Suitable For Vegetarians/Vegans Supplementing with 5-HTP provides natural support for emotional well-being, and caplets are time released to minimize gastric discomfort and optimize absorption. Natural Factors amino acids are the highest quality pharmaceutical grade products available. Isura®: Non-GMO: Documentation ✔ Mass Spec: Lab Tested ✔

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Dietary Supplement 5-Hydroxytryptophan Emotional Well-Being Suitable For Vegetarians/Vegans Supplementing with 5-HTP provides natural support for emotional well-being, and caplets are time released to minimize gastric discomfort and optimize absorption. Natural Factors amino acids are the highest quality pharmaceutical grade products available. Isura®: Non-GMO: Documentation ✔ Mass Spec: Lab Tested ✔

Customer reviews

5.0
verified purchase
Serotonin Savior!

I had to share how Natural Factors Stress-Relax 5-HTP has genuinely turned things around for me. These 60 time-release caplets have been my daily dose of tranquility. The benefits are crystal clear – I've noticed a major boost in my mood and a remarkable reduction in stress levels. It's like a natural stress-eject button! Recommending this to my friends and family has become a no-brainer, because everyone deserves to experience this sense of calm. If stress and mood swings have been a struggle, do yourself a favor and give 5-HTP a shot. Your mind and emotions will thank you!

8/27/2023
5.0
verified purchase
Ok

It seems to work for better sleep , but I always have the issue that new 5 HTP products only help for a while , then I have to stop for a few days ., but that I have with every kind and brand . I take it 1/2 before sleeping

4/20/2026
4.0
verified purchase
Helps me wind down

I started taking this mainly for sleep and stress, and it actually helps me feel more relaxed at night. The quality seems good and the ingredient blend feels simple and straightforward. The caplet size is a bit on the bigger side but still manageable. I like that it’s time release because it feels more steady, not too strong all at once. Packaging was fine, no issues. Overall, it’s been helpful for calming down before bed.

4/6/2026
5.0
verified purchase
Natural Factors, Stress-Relax, 5-HTP, 100 mg, 60 Time Release Caplets

I found the Natural Factors Stress-Relax 5-HTP to be a nice, gentle supplement that helped support mood and sleep without feeling too strong or artificial, and the 60 time-release caplets felt like a good amount for regular use. The time-release formula seems to help with smoother absorption and reduces stomach discomfort compared to some other 5-HTP pills I’ve tried, which is great if you’re sensitive to digestive issues. The ingredients are simple and clean — no artificial colors, preservatives, or fillers — and it’s suitable for vegetarians/vegans, which makes it feel like quality for the price. In terms of effectiveness, I noticed a slight improvement in my overall calmness and sleep quality after consistent use, though effects can be subtle and personal. The price is reasonable for a mood-support supplement and feels worth it if you want natural support without hype. Overall, it feels like a good, everyday product that does what it’s supposed to without fuss or weird side effects.

2/23/2026
5.0
verified purchase
Recommended to take for anxiety and sleep

I like that this is a time release formula for 5 HTP and ran out while on vacation. I believe it helps with calmness and mood and dietitian recommended I increase to 100 mg. Consumer Lab also tested and approved this brand for the ingredients.

1/18/2026
5.0
verified purchase
Good quality

I have take many vitamin for a long time. I think my health is good. I recommend to add this vitamin to.

12/26/2025
4.0
verified purchase
5-HTP

Natural Factors’ Stress‑Relax 5‑HTP is a high‑quality, time‑release or enteric‑coated supplement featuring 5‑Hydroxytryptophan (5‑HTP) sourced from Griffonia simplicifolia seed.  Each caplet delivers 50 mg or 100 mg of 5‑HTP, depending on version.  Ingredients are minimal: 5‑HTP, calcium (as dicalcium phosphate), cellulose, vegetable grade excipients; no artificial colours, gluten, dairy, soy or GMOs.  Dosage suggestion: 1 caplet, 2‑3 times daily with meals, starting low and increasing gradually over ~2 weeks to reduce digestive side effects.  Benefits include support for emotional well‑being, mood, stress relief and improved sleep. Potential downsides: increased risk of serotonin interaction (with SSRIs, MAOIs, etc.), possible nausea or gastric discomfort, and not suitable for pregnancy without medical advice. 

9/29/2025
5.0
verified purchase
Definitely works

I know this works because if i take it with less than 6 hrs of sleep time available, I wake up a little groggy. Nothing that doesn't go away within 30 minutes of waking, but definitely noticeable. As long as I have 6 hrs before needing to get up, there's no grogginess. Others may have different time frames.

9/20/2025
5.0
verified purchase

This supplement has been a miracle for me! I've had trouble sleeping since I entered menopause, and I posted on Facebook to ask my friends for advice. One of my friends suggested 5-htp and I ordered this brand.

7/27/2025
5.0
verified purchase
this product really saves my life for years now

I always suffered from anxiety, anger and mood and this product really helps me "keep head above water". its not a miracle drug but it actually works. recently i underwent a surgery and stopped taking it for several days and felt really bad mentally and it really surprised me how crucial it was for me to keep taking it. so I highly recommend trying but be aware when taking with other serotonin enhancers like SSRI drugs. p.s- it also somewhat reduces appetite and cravings.

4/6/2025