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Source Naturals

Coenzymated™ B-6, 30 Tablets

4.6 · 210 reviews
1,281 ₽

Dietary Supplement P-5'-P (Pyridoxal-5'-Phosphate) Brain, Heart, and PMS Support Suitable For Vegetarians 333 mg In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This more potent Coenzymated B-6 is in its active form; ready to go to work immediately. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6. It is primarily in the liver that P-5'-P is synthesized from vitamin B-6, with the help of enzymes that require B-2, zinc, and magnesium for their activity. P-5'-P activates over 100 enzymes, many of which are involved in the conversion of amino acids into the neurotransmitters dopamine, norepinephrine and serotonin. P-5'-P is also required for the synthesis of the hemoglobin molecule. It also plays an important role in regulating homocysteine levels.

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Dietary Supplement P-5'-P (Pyridoxal-5'-Phosphate) Brain, Heart, and PMS Support Suitable For Vegetarians 333 mg In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This more potent Coenzymated B-6 is in its active form; ready to go to work immediately. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6. It is primarily in the liver that P-5'-P is synthesized from vitamin B-6, with the help of enzymes that require B-2, zinc, and magnesium for their activity. P-5'-P activates over 100 enzymes, many of which are involved in the conversion of amino acids into the neurotransmitters dopamine, norepinephrine and serotonin. P-5'-P is also required for the synthesis of the hemoglobin molecule. It also plays an important role in regulating homocysteine levels.

Customer reviews

5.0
verified purchase
Excellent value and efficacy.

I've been buying this B6 supplement for many years. It is one of those supplement that you take where you can notice a difference and notice that its working. I take it before bed and my dream recall is vastly improved. This is a solid indicator for me that the supplement is working. Also the co-enzymated form is well worth it as many of us do not absorb well or convert well the standard B6. Lastly, the value for money is where this supplement really wins. Each tablet contains a whopping 333mg! This can be broken up into smaller doses as required. I actually cut it into approximate quarters in my mouth at the time of taking a tablet portion. They really go a long way for a supplement that noticeably works. 👍🏼Please like my review if you found it helpful.

7/6/2021
5.0
verified purchase
Lower prolactin

I’ve read that high dose B6 in p5p form can lower prolactin. I have above normal prolactin levels and was looking for a high dose pills so I take less pills. I’m happy to find this product that offers high potency 333 mg P5p in 1 capsule, and it’s still small enough to make it easy to swallow. Good quality product and well priced. Haven’t noticed any negative effects so I’m happy with that.

1/6/2024
5.0
verified purchase
Great!

I've been taking B6 for almost a year. This brand works as described. B6 in the form of p5p does not cause me any problems, just health benefits, no side effects in comparison to pyridoxine chloride (pyridoxine chloride gives me reactions of B6 toxicity even at low doses).BThe ingredients are good, does not have fillers I don't like. The price is affordable.

6/8/2025
5.0
verified purchase
helps to keep my mood stable

more potent Coenzymated B-6 is in its active form; ready to go to work immediately. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6.

8/4/2026
5.0
verified purchase
Good

I love how the quality of these pills are high, size is easy to swallow, nice ingredients, package is okay. Still need some time for the effects.

1/31/2026
4.0
verified purchase

Have no issues with this except if i dont tale enough magnesium along side it i get nauseous. Make sure to take p5p with magnesium if you also get nauseous taking it

11/9/2025
4.0
verified purchase
Take cautiously

I'm sure many people can take B-6 P5P without running into problem. Sensitive people can really react to it. It can have physical as well as psychological effects. That's not to say you shouldn't take it, but start slow and look for changes. If someone says or does something that bothers me, I usually let it go. When I'm taking B6 - not so much. It caused some rumination.

10/13/2025
5.0
verified purchase

The active P-5-P form of B6 has been highly affective for me without causing the toxicity that I experience with pyridoxine HCl (pyridoxine HCl causes me to have toxicity even at low doses). Plus, the price is great for the quality.

8/18/2025
5.0
verified purchase
High Potency B6

High quality ingredients. Package size is big enough for many months . I expect to see benefits in long run.

8/17/2025
5.0
verified purchase
Powerful and Effective B-6 Supplement!

Source Naturals Coenzymated B-6 is an excellent supplement! The active form of vitamin B-6, Pyridoxal-5'-Phosphate (P-5'-P), ensures immediate effectiveness, supporting brain health, heart function, and overall wellness. I appreciate the vegetarian-friendly formula and the absence of unnecessary additives. The tablets are easy to take, and I've noticed improvements in my energy levels and mental clarity since incorporating this into my routine. Highly recommend it for anyone seeking a potent and reliable B-6 supplement!

5/1/2025