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Vitamatic

P-5-P, 50 mg, 240 Tablets

4.9 · 62 reviews
1,804 ₽

Pyridoxal-5-Phosphate Formulated by Healthcare Professional GMP Quality Assured Dietary Supplement Non GMO Active Form of Vitamin B6 – P5P: Contains Pyridoxal-5-Phosphate, the bioactive form of Vitamin B6, for superior absorption and utilization by the body. Supports Energy & Nerve Health: Helps maintain energy production, brain health, and supports the nervous system for overall well-being.

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Pyridoxal-5-Phosphate Formulated by Healthcare Professional GMP Quality Assured Dietary Supplement Non GMO Active Form of Vitamin B6 – P5P: Contains Pyridoxal-5-Phosphate, the bioactive form of Vitamin B6, for superior absorption and utilization by the body. Supports Energy & Nerve Health: Helps maintain energy production, brain health, and supports the nervous system for overall well-being.

Customer reviews

5.0
verified purchase
Just What I Needed

P5P is the active, coenzyme form of Vitamin B6, essential for metabolizing proteins, fats, and carbohydrates, producing neurotransmitters, and supporting nerve function. Unlike common pyridoxine HCl, P5P does not require liver conversion, making it highly bioavailable. Typical dosages range from 50mg to 100mg daily. I actually take 25mg because I am small and that works for me. Easy to swallow, easy to divide. Take in AM though as can increase energy.

2/19/2026
5.0
verified purchase
An excellent supplement

Great quality and price. The size is easy to take. Will buy again

7/22/2026
4.0
verified purchase
Well packaged. Fast shipping and easy to track

Just started taking the tablet. I will observe and review later

7/10/2026
5.0
verified purchase
Active form, working dosage

A good option for vitamin B6 in the active form P-5-P. The 50 mg dosage is convenient for a course, and the large 240-tablet package is cost-effective and lasts a long time. The active form is better suited for those who prefer a pre-formed coenzyme form over regular pyridoxine. It can be useful for supporting the nervous system, metabolism, and overall well-being. The dosage is effective, so it's best to take it wisely and not exceed the recommended dosage.

5/28/2026
5.0
verified purchase
The Active Form Makes All the Difference

P-5-P — pyridoxal-5-phosphate — is the bioactive form of B6, and that distinction is the entire reason to choose it over standard pyridoxine. A meaningful portion of the population has reduced capacity to convert pyridoxine to its active form efficiently, which means standard B6 supplements are delivering less than the label implies. P-5-P skips that conversion step entirely and goes to work directly. Once you understand that, it's hard to justify going back to the inactive form.The quality from Vitamatic holds up well. Clean tablets, no unnecessary fillers padding out the ingredient list, and the potency at 50mg is in a range that's genuinely effective for supporting nervous system function, amino acid metabolism, and neurotransmitter synthesis without being reckless. B6 toxicity at very high doses is a real consideration, so a sensibly dosed product matters more here than with some other supplements.The effect on energy and metabolism is noticeable over consistent use — not in the acute, stimulant sense, but in the steadier, more sustainable way that proper cofactor availability tends to show up. B6 is involved in over a hundred enzymatic reactions, so sufficiency has wide-ranging downstream effects that are easy to underestimate.

4/14/2026
5.0
verified purchase

Vitamatic P-5-P 50 mg is excellent. The active form of B6 absorbs well and I notice better mood, sleep, and overall wellbeing. 240 tablets is fantastic value, clean product, and no side effects. Would buy again!

4/9/2026
5.0
verified purchase
good for cycle

Great of source good quality very health I feel the improvement and good taste thank you

4/6/2026
5.0
verified purchase
Reduced my tension headaches within days

If you find this helpful, please like this review! I will share more detailed experiences. I’ve suffered from tension headaches for over 10 years. After 4 days, frequency dropped from 4 times a week to about once. Compared to regular B6, this form works faster and feels stronger. Be careful not to overuse, as high doses may feel intense.

3/28/2026
5.0
verified purchase
Vitamatic P5P (pyridoxal‑5‑phosphate)

Vitamatic P5P (pyridoxal‑5‑phosphate): Vitamatic P5P uses the active form of vitamin B6, pyridoxal‑5‑phosphate, which your body can use directly without needing to convert it first. P5P is involved in over 100 biochemical reactions, including energy metabolism, neurotransmitter production (serotonin, dopamine, GABA), and amino acid processing. Because it doesn’t require liver conversion like regular B6, it can be more predictable and efficient for people with metabolic conversion issues.  Users typically take P5P for energy support, nervous system balance, mood regulation, and metabolic function. It’s generally well‑tolerated, though high doses may affect other cofactors like zinc and should be used thoughtfully.  In supplement form, it’s often valued for its bioavailability and direct usability compared with standard vitamin B6. 

3/24/2026
5.0
verified purchase

Good quality and ingredient a lot of benefit. package good.

3/1/2026