Dietary Supplement Sleep Sports Performance Stress Gluten Free Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter. Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus. Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation. In addition, studies also indicate GABA can enhance sleep. In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects. PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming. In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group. The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.
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Dietary Supplement Sleep Sports Performance Stress Gluten Free Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter. Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus. Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation. In addition, studies also indicate GABA can enhance sleep. In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects. PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming. In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group. The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.
SKU
3-18741
Brand
Thorne
Category
health / supplements / categories / amino-acids
Variants
1
Customer reviews
5.0
verified purchase
Incredibly helpful supplement that I wish I knew about sooner!
My mental health therapist friend recommended GABA (and particularly through Thorne) to me for relief from my morning mind-racing, and this 100mg has done exactly that! I monitor my sleep regularly via a smartwatch, and not only has my deep sleep increased, but I've slept a bit longer before the morning cortisol hits and my mind begins to race. My husband saw the changes I was experiencing and tried it himself a few months after I started, and he is SOLD on it as well as his sleep "rings" are off the charts now!
8/19/2025
5.0
verified purchase
Curb my alcohol craving
Yup, taking this for 2 weeks and my alcohol craving goes away
11/20/2025
5.0
verified purchase
I propose this to my own children
Very active, sometimes my children find it difficult to find down time and stay calm during school hours - which is a healthy sign in my view of healthy children, and not necessarily a sign of AdhD or other. Their diet is clean and they eat very little sugar and carbs - which seems normal here in Europe. So added to a healthy hygiene, I did see that this size of GABA has very clear benefits in bringing inner calm and focus. They ask for it before school, and in the evening, if sometimes difficult to wind down. I will be giving it to them for three months and we will assess again if needed next Spring.
9/5/2024
5.0
verified purchase
Quality
Good for sleeping . One of the best helps with my waking up at night
1/3/2026
5.0
verified purchase
Noticeable Calming Effect Without Grogginess
PharmaGABA-100 works well for promoting a calm, relaxed feeling without making me feel sleepy or foggy. I found it helpful during stressful days and in the evening to unwind. The capsules are easy to take and gentle on the stomach. High-quality product and consistent results, as expected from Thorne.
12/30/2025
5.0
verified purchase
Arrived well-packaged and exactly as described. The quality is good, works as expected, and fits easily into my daily routine. Good value for the price — would buy again.
12/1/2025
5.0
verified purchase
I feel noticeably calmer after using this for about a week.
11/17/2025
5.0
verified purchase
I’ve been taking Thorne GABA in the evenings and it helps me unwind and feel more relaxed before bed. The capsule is clean and easy to swallow, and though it doesn’t instantly knock me out, it does support smoother sleep and lower stress.
11/8/2025
5.0
verified purchase
Numbs me for sleep
I buy Thorne products all the time because of the quality and this product is no exception. Ingredients are well chosen for daily usage. I experienced zero negative effects. I think it is very good for sleeping, however you shall try first a smaller dosage to decide if it is right for you.
11/7/2025
5.0
verified purchase
you won't be disappointed
have ordered many bottles of this and i can always count on thorne product when it comes to formulation and quality of the transparent ingredients!
