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Life Extension

Melatonin, 6 Hour Timed Release, 300 mcg, 100 Vegetarian Tablets

4.7 · 1033 reviews
956 ₽

Gluten Free Non GMO LE Certified Promotes Optimal Sleep Dietary Supplement Melatonin is known to help you fall asleep. Our formula releases 300 mcg of melatonin over a period of six hours to help you fall asleep and stay asleep. What Is Melatonin 6 Hour Timed Release? Supplementing with melatonin has benefits beyond just sleep. Melatonin supports and modulates a healthy immune system response. It also supports cellular DNA and mitochondrial health, including by helping to inhibit oxidative damage. Melatonin increases the speed of falling asleep & promotes sleep quality, plus it has strong whole-body health benefits. Melatonin 6 Hour Timed Release Benefits Promotes optimal sleep with six-hour release formula Helps support circadian rhythm and immune function Helps promote cellular and DNA health Helps inhibit oxidative stress and protect mitochondria For occasional sleeplessness.

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Gluten Free Non GMO LE Certified Promotes Optimal Sleep Dietary Supplement Melatonin is known to help you fall asleep. Our formula releases 300 mcg of melatonin over a period of six hours to help you fall asleep and stay asleep. What Is Melatonin 6 Hour Timed Release? Supplementing with melatonin has benefits beyond just sleep. Melatonin supports and modulates a healthy immune system response. It also supports cellular DNA and mitochondrial health, including by helping to inhibit oxidative damage. Melatonin increases the speed of falling asleep & promotes sleep quality, plus it has strong whole-body health benefits. Melatonin 6 Hour Timed Release Benefits Promotes optimal sleep with six-hour release formula Helps support circadian rhythm and immune function Helps promote cellular and DNA health Helps inhibit oxidative stress and protect mitochondria For occasional sleeplessness.

Customer reviews

5.0
verified purchase
Works for me. Very slow release

First of all - with melatonin it is best to start small, and for me this small amount works very well. After menopause my sleep disorder turned into a little monster and I found myself tossing and turning all night and finally waking up much too early. I was tired all day and just lacked energy for my life. It was awful. I now take one tablet of this melatonin just when I go go bed. With it I take one capsule of Jarrow's sleeping formula. This combination gives me 7-10 hours of deep undisturbed sleep!!! Excellent sleep quality and I wake up with bags of energy. The tabled is quite small so it is easy to swallow. I try not to take it later than 10pm otherwise it gives me a headachy morning. Every 10-14 days I feel very tired in the evening so I don't take anything that night. I then don't take any for the next night too and that way I have the recommended breaks in melatonin intake

2/26/2021
5.0
verified purchase
Ultra low dose

For me this works better than any high dosage melatonin I've tried. it does not leave me hazy the next day or give me symptoms of depression like the high dose ones. This brand is known for quality ingredients. I really appreciate the time release as well, it seems to work well.

10/19/2025
5.0
verified purchase
Sustained release a rarity

Many melatonin supplements tout themselves as sustained release, but only this leaves up to the promise. Won’t wake up at 3am like how I used to. I’ve tried like 3 brands and this is the real deal. I love all Life Extension products it was first introduced by my orthopedic surgeon so I find this brand more legit. I take it 1 hour before sleep. And preferably on an empty stomach for it to work best. So no late night supper. At least for me

5/5/2025
5.0
verified purchase
Perfect amount of dose.

Melatonin is produced by the pineal gland in our brain and on average the pineal gland produces 0.1mg to 0.8mg of melatonin at night. Hence why 300mcg for me is the perfect dose. No crazy dreams and it’s enough for my body to handle. My doctor even said that it can actually mess my circadian rhythm and it can cause a lot of other health issues if I’m taking such high dosage. Other than that, this supplement came in small bottle so I can bring it anywhere easily and it was sealed properly so no need to worry about the quality.

12/25/2024
5.0
verified purchase
Six Hour Melatonin

If you've looked for time release melatonin, you know most brands last only 4 hours. This melatonin actually helps me get 6-7 hours of sleep. No other brand has helped me maintain sleep this long. They are easy to swallow coated tablets.

8/19/2026
5.0
verified purchase
Best melatonin formula

I've been using this specific formulation for years. A lot of people think the higher the dose of melatonin, the better. But extremely low doses are actually more effective, and the time-release formula saves me from those 3am wake-ups. Customer for life.

8/19/2026
5.0
verified purchase
Excellent

Best way to have good sleep with melatonine is to have it time released and then the natural amount which is for me around this. Very advisabe!

3/31/2026
5.0
verified purchase
Great product

Love it! It's just a right quality for me. 100 tablets last over 3 months. Very good price for such a high quality product

3/25/2026
5.0
verified purchase

Supplement name: Life Extension, Melatonin, 6 Hour Timed Release, 300 mcg, 100 Vegetarian Tablets Supplement scores: 8 Introduction & context: Melatonin, a hormone regulating sleep-wake cycles, is commonly used for insomnia and jet lag. This product offers 300 mcg per tablet with a 6-hour timed-release mechanism, priced around $0.10 per serving. Third-party testing by NSF confirms purity and label accuracy. Evidence summary: Numerous RCTs support melatonin's efficacy in reducing sleep onset latency, particularly in delayed sleep phase disorder and jet lag. A 2017 meta-analysis (195 studies) found doses “”1 mg effective, with 3 mg showing marginal additional benefit. However, trials rarely exceed 3 mg, raising questions about the necessity of 300 mcg. Formulation & quality analysis: The 300 mcg dose aligns with lower-end effective studies but exceeds typical recommendations. Timed-release may benefit sustained sleep but lacks direct comparative evidence. Vegetarian tablets include microcrystalline cellulose and stearic acid; no major concerns. Safety & interactions: Generally safe; mild side effects include drowsiness and headache. Caution advised for pregnant/lactating women and those on sedatives. Potential interactions with anticoagulants and immune-suppressants. Personal experience after taking the product: Effective for reducing sleep onset time without morning grogginess at the tested dose. Value & practicality: Cost-effective for those needing lower doses. Alternatives include immediate-release formulations for flexibility. Overall verdict + score: Strong evidence and quality support its use for specific sleep issues. Suitable for individuals requiring precise dosing control. 8/10 Who it's for: Those with delayed sleep phase disorder or jet lag seeking a controlled release. I would consider it, opting for lower doses if effective.

3/12/2026
5.0
verified purchase
Reliable Timed-Release Melatonin

This 300 mcg timed-release melatonin supports restful sleep throughout the night. The tablets are small and easy to swallow. The timed-release formula provides a gentle dose without grogginess, helping maintain a healthy sleep cycle. The ingredients are high quality with consistent potency. Packaging is secure and the bottle size is convenient for travel. Overall a dependable supplement for better sleep and recovery.

11/19/2025