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Source Naturals

Coenzymated™ B-6, 25 mg, 120 Lozenges

4.8 · 1114 reviews
1,586 ₽

Dietary Supplement P-5'-P (Pyridoxal-5'-Phosphate) Supports Amino Acid Metabolism The Benefits of Coenzymated™ Vitamins In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This Coenzymated™ B-6 goes directly into your bloodstream in its active form, ready to go to work immediately. This avoids the loss that may occur not only during digestion, but during the liver's conversion process as well. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6. It is primarily in the liver that P-5'-P is synthesized from pyridoxine, with the help of enzymes that require B-2, zinc and magnesium for their activity. P-5'-P is associated with numerous enzymes, many of which are involved in the conversion of amino acids into the neurotransmitters dopamine, norepinephrine and serotonin. P-5'-P is also required for the synthesis of the hemoglobin molecule.

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Dietary Supplement P-5'-P (Pyridoxal-5'-Phosphate) Supports Amino Acid Metabolism The Benefits of Coenzymated™ Vitamins In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This Coenzymated™ B-6 goes directly into your bloodstream in its active form, ready to go to work immediately. This avoids the loss that may occur not only during digestion, but during the liver's conversion process as well. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6. It is primarily in the liver that P-5'-P is synthesized from pyridoxine, with the help of enzymes that require B-2, zinc and magnesium for their activity. P-5'-P is associated with numerous enzymes, many of which are involved in the conversion of amino acids into the neurotransmitters dopamine, norepinephrine and serotonin. P-5'-P is also required for the synthesis of the hemoglobin molecule.

Customer reviews

5.0
verified purchase
Great

On the advice of research scientists, I take vitamin B6 in courses along with magnesium. For example, I add it to a supplement - MAGNESIUM OROTATE, which is useful for heart health, or MAGNESIUM TAURATE, which is important for normalizing blood pressure and good eyesight, or MAGNESIUM GLYCINATE, which calms the nervous system and promotes good sleep, or MAGNESIUM THREONATE, which improves brain activity, or MAGNESIUM CITRATE, which dissolves kidney stones and helps in intestinal cleansing, or MAGNESIUM MALATE, is wonderfully invigorating!

9/28/2024
5.0
verified purchase
Helps me a lot

The coenzymated form of Vitamin B6 was a significant upgrade in my supplement routine. Its enhanced absorption was crucial for me, given the digestive challenges posed by IBS. B6 is vital for many bodily functions, including neurotransmitter synthesis and energy metabolism. Since incorporating it, I've noticed an improvement in my mood and energy levels, which had often been low due to my ongoing health issues.

2/2/2024
5.0
verified purchase
Sublingual absorbs best

I take B6 for nervous system issues but it can cause problems in high amounts, so I prefer smaller doses and Source Naturals seems to be one of the few brands that carries smaller dose pills. Sublingual is also a plus because it absorbs better and it's less pills to take. So what is not to like. It's effective, easy to take and cheap.

1/22/2024
5.0
verified purchase
Great P5P

This P5P is great. I really like supplements in lozenge form. They seem to be absorbed much better than capsules. With this one, I can feel the difference within minutes of taking it. It gives me more mental clarity and improves my concentration. Whereas when I take P5P capsules I feel no difference.

9/14/2023
4.0
verified purchase
Alright

The taste is okay on these. It's not the best, there are a few other brands that have a better taste but the ingredients aren't bad and I prefer getting my supplements from somewhere that I can trust a little bit more than other places that don't have a guarantee. The quality seems pretty good. I just started taking them so can't say if it's helped or not.

6/30/2026
3.0
verified purchase
Fine. But dose is too high and don't like flavor.

I don't like mint flavoring, for the most part, and definitely not this particular mint. And I wish the dose was about 1/4 of this because it is possible to get too much B-6. If I took one/day, that would likely be too much. But it's nice to have a lozenge I can just cut into 1/4ths.

3/8/2026
5.0
verified purchase
The best for me

Coenzymated b6 ,it is the biologically active coenzyme form of Vitamin B6.Vitamin p5p helps maintain normal homocysteine levels, which is crucial for heart health.

2/1/2026
5.0
verified purchase
Greast product

I’ve been taking Source Naturals Coenzymated B-6 25 mg and the quality is excellent. The active ingredient absorbs well, and the lozenge size is really easy to use. The package is compact with plenty of tablets inside, and the potency feels perfect for daily support. I notice better energy and a calm nervous system, plus a positive effect on my metabolism. There’s no niacin flush or anything uncomfortable, and the taste is mild and pleasant under the tongue. It also doesn’t rely on synthetic folic acid, which I appreciate. A great everyday B-6 supplement that feels gentle but genuinely effective.

12/7/2025
5.0
verified purchase
Waiting to taste this metabolism magic quality ingredient

Why take folic acid? It is not bioavailable. This package should not contain any. There shouldn't be any niacin flush either. Not sure why iHerb suggests these as key words to describe this product.

11/29/2025
5.0
verified purchase

good quality, great ingredients, more energy thanks for b-6. nice effect

11/9/2025