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Natural Factors

BioCoenzymated®, 5-MTHF Plus Methylcobalamin, 60 Quick-Dissolve Tablets

4.8 · 1500 reviews
1,714 ₽

Dietary Supplement Folate + B12 1000 mcg Plus Methylcobalamin B12 50 mcg The Most Metabolically Active Form Suitable For Vegetarians Why Choose BioCoenzymated? B vitamins are like tiny keys that unlock and activate countless vital biochemical functions throughout your body. Unfortunately, many factors can limit the conversion of B vitamins to their active forms. Taking B vitamins in their bioactive coenzymated form means there are no complicated conversions your body needs to make. Coenzymated B vitamins allow your body to quickly and directly absorb and use these essential vitamins. This also means that your body needs less to achieve the same benefits as non-coenzymated forms. Feel the difference with BioCoenzymated 5-MTHF plus Methylcobalamin! Supports cardiovascular health Supports or maintains nerve health Gluten-free Promotes immune health Non-GMO Third-party certified for purity and potency BioCoenzymated 5-MTHF plus Methylcobalamin combines these two powerful vitamins and upgrades them to their biologically active forms. Supports cardiovascular, immune, and neurological health. Vitamin B12 helps produce red blood cells. Supports the majority of the population that is unable to convert folic acid to its active form. The Isura® seal is your assurance that this product is independently verified as clean and safe, and has been tested for over 800 possible contaminants. Isura's rigorous testing includes hundreds of quality procedures using state-of-the-art technology. It provides you with the confidence that this product is Isura verified clean, one of the highest testing standards in the world. Isura®: Verified Clean: ✔ Non-GMO: ✔

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Dietary Supplement Folate + B12 1000 mcg Plus Methylcobalamin B12 50 mcg The Most Metabolically Active Form Suitable For Vegetarians Why Choose BioCoenzymated? B vitamins are like tiny keys that unlock and activate countless vital biochemical functions throughout your body. Unfortunately, many factors can limit the conversion of B vitamins to their active forms. Taking B vitamins in their bioactive coenzymated form means there are no complicated conversions your body needs to make. Coenzymated B vitamins allow your body to quickly and directly absorb and use these essential vitamins. This also means that your body needs less to achieve the same benefits as non-coenzymated forms. Feel the difference with BioCoenzymated 5-MTHF plus Methylcobalamin! Supports cardiovascular health Supports or maintains nerve health Gluten-free Promotes immune health Non-GMO Third-party certified for purity and potency BioCoenzymated 5-MTHF plus Methylcobalamin combines these two powerful vitamins and upgrades them to their biologically active forms. Supports cardiovascular, immune, and neurological health. Vitamin B12 helps produce red blood cells. Supports the majority of the population that is unable to convert folic acid to its active form. The Isura® seal is your assurance that this product is independently verified as clean and safe, and has been tested for over 800 possible contaminants. Isura's rigorous testing includes hundreds of quality procedures using state-of-the-art technology. It provides you with the confidence that this product is Isura verified clean, one of the highest testing standards in the world. Isura®: Verified Clean: ✔ Non-GMO: ✔

Customer reviews

5.0
verified purchase

Methyl Folate is a natural and active form (please, never take synthetic folic acid, it doesn't give you any benefits but may be harmful). The human body needs folate to perform many functions, including cell division, growth, and the production of new red blood cells. It could help improve the language and communication skills of children with ASD. It is also must have for everybody who takes big doses of MB12. The price is affordable. Be healthy!

11/3/2021
5.0
verified purchase

Good vitamins, excellent composition. Folic acid is in the best form and the dosage is excellent. Vitamin B12 is also in the composition, I have a big shortage of tests. A huge plus is that Natural Factors vitamins are natural. A wonderful drug, easy to take, and when they are taken as prescribed, they work very well. An excellent manufacturer. The quality is excellent. The taste is pleasant. The result is excellent. The packaging is good. The tablet size is small, it is convenient to take

9/13/2023
5.0
verified purchase

I started to trust the natural factors company. They don't add redundant fillers like stearate or silica or silicon dioxide. I like it. Also, their recent products consider higher bioavailability rate of thr supplements, not just regular supplements. I want to assist methylation so I bought the product and the pill size is extremely tiny tiny! Very easy to swallow. I learned it's a better form than folic acid and probably the best way to provide folic acid I guess. Tiny pill doesn't give you enough time to give it justice about the taste. 😙 I think it will help with cell metabolism and nervous system, both of which I need. So i think I am benefiting from it. Thanks.

2/19/2023
5.0
verified purchase
best ever

This products works super and imediatly with my son .High quality ingredients and perfect size and taste.The effect and it's potency you remark imediatly after usage and great for nervous system. We started with half tablet in morning and half in night and then after 2 weeks we increased it to 1 tab day and 1 night.

11/3/2025
5.0
verified purchase
great source of b vitamins

Quality ingredient. Small size. Good potency. Helps with my metabolism

11/30/2024
5.0
verified purchase
Eureka

I have recently been tracking my nutrient and micronutrients. I could not get my B12 and folate to register what I needed per day. Maybe it's the app, but my energy level was not where I wanted it to be as well. I set out to find a supplement that would help. When I came this and looked at the ingredients, it was spot on with some of the best sources and fit my WFPB lifestyle. the package did say it contained milk and although I am dairy free for the life of me I can't figure out what source it would be coming from but it can't be much so I'm okay with that.

10/25/2024
5.0
verified purchase
Good

Gets the job done for me, but next time I'm getting something without B12 or less of it because the dosage is a bit too high and exacerbates acne for me.

6/13/2026
5.0
verified purchase

Good product with good ingredients and size, with the exact package and quality and benefits

4/8/2026
5.0
verified purchase

8.0 stars Natural Factors, BioCoenzymated®, Folate + B12, 60 Quick-Dissolve Tablets delivers solid evidence for methylation support and cognitive health. Each tablet provides 400 mcg of 5-methyltetrahydrofolate (5-MTHF) and 500 mcg of methylcobalamin—the bioactive forms of folate and B12, bypassing conversion inefficiencies seen in folic acid and cyanocobalamin. This aligns with studies showing enhanced serum folate and plasma B12 levels (Cmax – 20–30% higher vs. synthetic forms). Third-party testing by NSF confirms label accuracy and absence of contaminants like lead. The quick-dissolve format aids absorption, though AUC0-t data specific to these forms is limited. Bioavailability is generally high, especially for individuals with MTHFR polymorphisms. Safety is well-established at these doses; however, B12’s long half-life necessitates monitoring in renal impairment. At $0.23/dose, it’s cost-effective. Recommended for those with absorption issues or elevated homocysteine. I’d consider it if needed, but dietary sources should remain primary.

2/16/2026
5.0
verified purchase
great

i have adrenal fatigue and i have beeb taking this for nervous system and anxiety

12/16/2025